Molecular Biologist

Apex Systems • Full-time • Ambler, Pennsylvania, United States • 8h ago

Cell Biologist
We are seeking trailblazers, motivated to deliver innovative solutions, who are enthusiastic collaborators, driven by a sense of urgency to assist patients.
Code Biotherapeutics is a privately-held biotechnology company pioneering the development of genetic medicines to treat and potentially cure serious and life-threatening genetic diseases. Code Bio leverages its proprietary, novel multivalent synthetic DNA delivery platform, 3DNA®, which has been engineered to overcome many of the challenges inherent with viral-based gene therapies such as immunogenicity, gene of interest size and delivery limitations, ability to re-dose, and vector manufacturing complexity. The Company is advancing an internal pipeline focused on selecting diseases without a cure, as well as establishing partnerships to take forward programs in both rare and prevalent diseases.

Key Responsibilities:
The primary responsibilities of this position include, but are not limited to:

Work independently and as part of an interdisciplinary team to support thedevelopment and evaluation of non-viral gene therapies using the company's novel DNA scaffold technology.

Molecular characterization of biomolecules including DNA-conjugated modalities including peptides, antibodies, proteins, and small molecules.
Test various molecules and modalities for biochemical suitability, potential efficacy and safety using cell-based assays combined with various analytical methods.
Develop cell and molecular assays to assess cell fate, potency and durability of the delivery scaffold and genetic payloads.
Design and test cell-based protocols for transfer to the Development team.
Maintain data acquisition and analysis in electronic laboratory notebook.

Basic Qualifications:

- - BS degree in Cell Biology, Molecular Biology, Biochemistry, Pharmaceutical Sciences with 3-5 years or a MS degree with 0-3 years of research and development experience.
  - Experience with mammalian cell culture and knowledge on cell based assays.
  - Detail-oriented with strong organizational and communication skills.
  - Experience with DNA and RNA extraction methods and downstream use.
  - Hands-on experience with standard laboratory equipment and procedures.
  - Able to digest complex articles and reviews and pull relevant information, ideas, and methodologies for experimental use.
  - General understanding of cell-based assays and outcomes.
  - Knowledge of peptide and protein structure and function.
  - Basic analytical characterization methods.

Preferred Skills/Experience:

Experience with flow cytometry cell-based assays for quantitative assessment of results.
Experience with qPCR, ddPCR and other qualitative and quantitative nucleic acid analysis methodologies.
Experience in performing plate and bead-based pulldown and analytical assays.
Able to troubleshoot experiments and instrument issues.

Code Bio is committed to equal employment opportunity and non-discrimination for all employees and qualified applicants without regard to a person's race, color, gender, age, religion, national origin, ancestry, disability, veteran status, genetic information, sexual orientation, or any characteristic protected under applicable law. Code Bio will make reasonable accommodations for qualified individuals with known disabilities, in accordance with applicable law.
In addition, Code Bio is committed to social responsibility and developing an inclusive culture. Much like the development of our novel delivery of genetic medicines, we believe that our work requires the creativity and ingenuity of a diverse workforce, and we are committed to pursuing that in all facets of the work experience at Code Bio. We will continue to educate ourselves about the inequities and barriers present in our society and act as a company where we can make a difference.
Code Bio is proud to be an Equal Opportunity Employer.

EEO Employer

Apex Systems is an equal opportunity employer. We do not discriminate or allow discrimination on the basis of race, color, religion, creed, sex (including pregnancy, childbirth, breastfeeding, or related medical conditions), age, sexual orientation, gender identity, national origin, ancestry, citizenship, genetic information, registered domestic partner status, marital status, disability, status as a crime victim, protected veteran status, political affiliation, union membership, or any other characteristic protected by law. Apex will consider qualified applicants with criminal histories in a manner consistent with the requirements of applicable law. If you have visited our website in search of information on employment opportunities or to apply for a position, and you require an accommodation in using our website for a search or application, please contact our Employee Services Department at [email protected] or 844-463-6178 .

Apex Systems is a world-class IT services company that serves thousands of clients across the globe. When you join Apex, you become part of a team that values innovation, collaboration, and continuous learning. We offer quality career resources, training, certifications, development opportunities, and a comprehensive benefits package. Our commitment to excellence is reflected in many awards, including ClearlyRated's Best of Staffing® in Talent Satisfaction in the United States and Great Place to Work® in the United Kingdom and Mexico.